SRGN Antibody

CATALOG NUMBER: 56-327

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SRGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human SRGN.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SRGN
Additional Names:
Serglycin, Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, PPG, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1
Protein Accession Number:
P10124
Protein Gi Number:
269849659
Ncbi Gene Id Number:
5552
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein best known as a hematopoieticcell granule proteoglycan. Proteoglycans stored in the secretorygranules of many hematopoietic cells also contain aprotease-resistant peptide core, which may be important forneutralizing hydrolytic enzymes. This encoded protein was found tobe associated with the macromolecular complex of granzymes andperforin, which may serve as a mediator of granule-mediatedapoptosis. Two transcript variants, only one of themprotein-coding, have been found for this gene. [provided byRefSeq].
Background Reference 1:
Ma, D., et al. Pediatr Blood Cancer 50(5):1067-1069(2008)
Background Reference 2:
Kolset, S.O., et al. Glycoconj. J. 25(4):305-311(2008)
Background Reference 3:
Theocharis, A.D., et al. J. Biol. Chem. 281(46):35116-35128(2006)
Background Reference 4:
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-327

List Size:
400 ul

List Price:

$469.00

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