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Western blot analysis of E coli derived SRP54 fusion protein using XW-7589 at 1:2,000.
Western blot analysis of E coli derived SRP54 fusion protein using XW-7589 at 1:2,000.

SRP54 Antibody

CATALOG NUMBER: XW-7589

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
300-504
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
SRP54 antibody can be used for the detection of SRP54 by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
55.7 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
SRP54 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SRP54
Additional Names:
Signal recognition particle 54 kDa proteinSRP54, SRP54
Protein Accession Number:
NP_003127.1
Protein Gi Number:
4507215
Ncbi Gene Id Number:
6729
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Human signal recognition particle 54kDa. The signal recognition particle (SRP) is an oligomeric complex that mediates targeting and insertion of the signal sequence of exported proteins into the membrane of the endoplasmic reticulum. SRP consists of a 7S RNA and six protein subunits. 54 kD protein (SRP54) is one of these subunits. It is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. The 54K subunit of the signal recognition particle has a two domain structure: the G-domain that binds GTP and the M-domain that binds the 7s RNA and also binds the signal sequence. The N-terminal 300 residues of SRP54 include the GTP-binding site (G-domain) and are evolutionary related to similar domains in other proteins.
Background Reference 1:
Pool, M. R., Stumm, J., Fulga, T. A., Sinning, I., Dobberstein, B. Distinct modes of signal recognition particle interaction with the ribosome. Science 297: 1345-1348, 2002.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7589

List Size:
0.05 mg

List Price:

$615.00

Out of stock

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