SSH1 Antibody

CATALOG NUMBER: 60-530

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human SSH1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
116 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSH1
Additional Names:
Protein phosphatase Slingshot homolog 1, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L
Protein Accession Number:
Q8WYL5
Protein Gi Number:
82582267
Ncbi Gene Id Number:
54434
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The ADF (actin-depolymerizing factor)/cofilin family (seeMIM 601442) is composed of stimulus-responsive mediators of actindynamics. ADF/cofilin proteins are inactivated by kinases such asLIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears toplay a role in actin dynamics by reactivating ADF/cofilin proteinsin vivo (Niwa et al., 2002 [PubMed 11832213]).
Background Reference 1:
Song, S.Y., et al. APMIS 118(5):389-393(2010)
Background Reference 2:
Peterburs, P., et al. Cancer Res. 69(14):5634-5638(2009)
Background Reference 3:
Kligys, K., et al. Biochem. Biophys. Res. Commun. 383(4):450-454(2009)
Background Reference 4:
Kim, J.S., et al. Mol. Biol. Cell 20(11):2650-2660(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-530

List Size:
400 ul

List Price:

$495.00

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