SSR4 Antibody

CATALOG NUMBER: 58-470

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SSR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human SSR4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
19 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSR4
Additional Names:
Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta, SSR4, TRAPD
Protein Accession Number:
P51571
Protein Gi Number:
1711550
Ncbi Gene Id Number:
6748
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SSR4, also called TRAPD, is assumed to be involved inprotein secretion. It is located in the Xq28 region, arranged in acompact head-to-head manner with the IDH3G gene. These two genesare driven by a bidirectional promoter located between them, andencode proteins involved in unrelated biochemical pathways locatedin different compartments of the cell. The nontranscribedintergenic region represents only 133 bp and is embedded in a CpGisland. The CpG island functions as a bidirectional promoter toinitiate the transcription of both functionally unrelated geneswith distinct expression patterns. SSR4 consists of six exons andis approximately 70 kb telomeric to the ALD gene. Althoughalternative splicing of exon 5 has not been detected in human SSR4,transcript variants missing the region homologous to human exon 5have been detected in both Xenopus laevis and Mus musculus.
Background Reference 1:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 2:
Wang, Z., et al. Melanoma Res. 14(2):107-114(2004)
Background Reference 3:
Miyazaki, K., et al. J. Biol. Chem. 279(12):11327-11335(2004)
Background Reference 4:
Wang, L., et al. FEBS Lett. 457(3):316-322(1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-470

List Size:
400 ul

List Price:

$495.00

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