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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

SSRP1 Antibody

CATALOG NUMBER: 58-023

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SSRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the C-terminal region of human SSRP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSRP1
Additional Names:
FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, FACT 80 kDa subunit, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, hSSRP1, T160, SSRP1, FACT80
Protein Accession Number:
Q08945
Ncbi Gene Id Number:
6749
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a subunit of aheterodimer that, along with SUPT16H, forms chromatintranscriptional elongation factor FACT. FACT interacts specificallywith histones H2A/H2B to effect nucleosome disassembly andtranscription elongation. FACT and cisplatin-damaged DNA may becrucial to the anticancer mechanism of cisplatin. This encodedprotein contains a high mobility group box which most likelyconstitutes the structure recognition element forcisplatin-modified DNA. This protein also functions as aco-activator of the transcriptional activator p63. An alternativelyspliced transcript variant of this gene has been described, but itsfull-length nature is not known.
Background Reference 1:
Zeng, S.X., et al. Mol. Cell. Biol. 30(4):935-947(2010)
Background Reference 2:
Hautbergue, G.M., et al. Curr. Biol. 19(22):1918-1924(2009)
Background Reference 3:
Hu, J., et al. J. Virol. 83(21):11051-11063(2009)
Background Reference 4:
Kumari, A., et al. J. Cell. Biochem. 108(2):508-518(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-023

List Size:
400 ul

List Price:

$495.00

Datasheet
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