SSTR5 Antibody

CATALOG NUMBER: 60-259

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SSTR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human SSTR5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSTR5
Additional Names:
Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R, SSTR5
Protein Accession Number:
P35346
Protein Gi Number:
12644225
Ncbi Gene Id Number:
6755
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Somatostatin and its related peptide cortistatin exertmultiple biological actions on normal and tumoral tissue targets byinteracting with somatostatin receptors (SSTRs). The proteinencoded by this gene is one of the SSTRs, which is a multi-passmembrane protein and belongs to the G-protein coupled receptor 1family. The activity of this receptor is mediated by G proteinswhich inhibit adenylyl cyclase, and different regions of thisreceptor molecule are required for the activation of differentsignaling pathways. A mutation in this gene results in somatostatinanalog resistance. Alternatively spliced transcript variants havebeen identified in this gene.
Background Reference 1:
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Background Reference 2:
Saus, E., et al.Psychiatr Res 44(14):971-978(2010)
Background Reference 3:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 4:
Duran-Prado, M., et al. J. Clin. Endocrinol. Metab. 95(5):2497-2502(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-259

List Size:
400 ul

List Price:

$495.00

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