SSX3 Antibody

CATALOG NUMBER: 59-853

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSX3
Additional Names:
Protein SSX3, Cancer/testis antigen 53, CT53, SSX3
Protein Accession Number:
Q99909
Protein Gi Number:
84028266
Ncbi Gene Id Number:
10214
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the family of highlyhomologous synovial sarcoma X (SSX) breakpoint proteins. Theseproteins may function as transcriptional repressors. They are alsocapable of eliciting spontaneously humoral and cellular immuneresponses in cancer patients, and are potentially useful targets incancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes havebeen involved in the t(X;18) translocation characteristically foundin all synovial sarcomas. This gene appears not to be involved inthis type of chromosome translocation. Two transcript variantsencoding distinct isoforms have been identified for this gene.
Background Reference 1:
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Background Reference 2:
Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)
Background Reference 3:
de Bruijn, D.R., et al. Genes Chromosomes Cancer 34(3):285-298(2002)
Background Reference 4:
Gure, A.O., et al. Int. J. Cancer 72(6):965-971(1997)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-853

List Size:
400 ul

List Price:

$495.00

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