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Western blot analysis in CEM,K562,NCI-H292,MDA-MB453,A549 cell line lysates (35ug/lane).
Western blot analysis in CEM,K562,NCI-H292,MDA-MB453,A549 cell line lysates (35ug/lane).

SSX4 Antibody

CATALOG NUMBER: 56-923

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human SSX4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SSX4
Additional Names:
Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A
Protein Accession Number:
O60224
Ncbi Gene Id Number:
5483136759
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the family of highlyhomologous synovial sarcoma X (SSX) breakpoint proteins. Theseproteins may function as transcriptional repressors. They are alsocapable of eliciting spontaneously humoral and cellular immuneresponses in cancer patients, and are potentially useful targets incancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes havebeen involved in the t(X;18) translocation characteristically foundin all synovial sarcomas. This translocation results in the fusionof the synovial sarcoma translocation gene on chromosome 18 to oneof the SSX genes on chromosome X. Chromosome Xp11 contains asegmental duplication resulting in two identical copies of synovialsarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tailorientation. This gene, SSX4B, represents the more centromericcopy. Two transcript variants encoding distinct isoforms have beenidentified for this gene.
Background Reference 1:
Ayyoub, M., et al. J. Immunol. 174(8):5092-5099(2005)
Background Reference 2:
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Background Reference 3:
Gure, A.O., et al. Int. J. Cancer 101(5):448-453(2002)
Background Reference 4:
Brodin, B., et al. Gene 268 (1-2), 173-182 (2001) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-923

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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