ST6GALNAC4 Antibody

CATALOG NUMBER: 60-240

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ST6GALNAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human ST6GALNAC4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ST6GALNAC4
Additional Names:
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase, NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV, ST6GalNAcIV, Sialyltransferase 3C, SIAT3-C, Sialyltransferase 7D, SIAT7-D, ST6GALNAC4, SIAT3C, SIAT7D
Protein Accession Number:
Q9H4F1
Protein Gi Number:
21759443
Ncbi Gene Id Number:
27090
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a type II membraneprotein that catalyzes the transfer of sialic acid from CMP-sialicacid to galactose-containing substrates. The encoded proteinprefers glycoproteins rather than glycolipids as substrates andshows restricted substrate specificity, utilizing only thetrisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. Inaddition, it is involved in the synthesis of ganglioside GD1A fromGM1B. The encoded protein is normally found in the Golgi apparatusbut can be proteolytically processed to a soluble form. Thisprotein is a member of glycosyltransferase family 29. Transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Yoshino, H., et al. Brain Res. 1227, 216-220 (2008) :
Background Reference 2:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 3:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 4:
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-240

List Size:
400 ul

List Price:

$495.00

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