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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

STAR Antibody

CATALOG NUMBER: 58-562

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This STAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human STAR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
32 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
STAR
Additional Names:
Steroidogenic acute regulatory protein, mitochondrial, StAR, START domain-containing protein 1, StARD1, STAR, STARD1
Protein Accession Number:
P49675
Protein Gi Number:
71152974
Ncbi Gene Id Number:
6770
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene plays a key role in theacute regulation of steroid hormone synthesis by enhancing theconversion of cholesterol into pregnenolone. This protein permitsthe cleavage of cholesterol into pregnenolone by mediating thetransport of cholesterol from the outer mitochondrial membrane tothe inner mitochondrial membrane. Mutations in this gene are acause of congenital lipoid adrenal hyperplasia (CLAH), also calledlipoid CAH. A pseudogene of this gene is located on chromosome 13.
Background Reference 1:
Shi, F.T., et al. J. Clin. Endocrinol. Metab. 95 (10), E172-E180 (2010) :
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Mizutani, T., et al. J. Biol. Chem. 285(36):28240-28251(2010)
Background Reference 4:
Sahakitrungruang, T., et al. J. Clin. Endocrinol. Metab. 95(7):3352-3359(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-562

List Size:
400 ul

List Price:

$495.00

Datasheet
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