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Western blot analysis of lysed extracts from HeLa cells using STAT3 (Phospho-Tyr705).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Phospho-Tyr705).
Western blot analysis of lysed extracts from HeLa cells using STAT3 (Phospho-Tyr705).

STAT3 (phospho Tyr705) Antibody

CATALOG NUMBER: 79-122

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
STAT3 (Phospho-Tyr705) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 705 (A-P-Y (p) -L-K) derived from Human STAT3.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of STAT1 only when phosphorylated at serine 727.
Predicted Molecular Weight:
88 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
STAT3
Additional Names:
APRF, HIES, STAT5, APRF, Acute-phase response factor
Protein Accession Number:
NP_003141.2
Protein Gi Number:
21618338
Ncbi Gene Id Number:
6774
Background:
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
Background Reference 1:
Fan G, et al. (2003) J Biol Chem. 278 (52): 52432-52436. Barry FA, et al. (2003) FEBS Lett. 553 (1-2): 173-178. Welsh, et al. (1996) Trends Cell Biol. 6: 274-279. Srivastava A K, et al. (1998) Mol Cell Biochem. 182: 135-141.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-122

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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