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Western blot analysis in mouse heart tissue lysates (35ug/lane).
STC2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in mouse heart tissue lysates (35ug/lane).

STC2 Antibody

CATALOG NUMBER: 57-642

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
STC2
Additional Names:
Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2
Protein Accession Number:
O76061
Ncbi Gene Id Number:
8614
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a secreted, homodimeric glycoproteinthat is expressed in a wide variety of tissues and may haveautocrine or paracrine functions. The encoded protein has 10 of its15 cysteine residues conserved among stanniocalcin family membersand is phosphorylated by casein kinase 2 exclusively on its serineresidues. Its C-terminus contains a cluster of histidine residueswhich may interact with metal ions. The protein may play a role inthe regulation of renal and intestinal calcium and phosphatetransport, cell metabolism, or cellular calcium/phosphatehomeostasis. Constitutive overexpression of human stanniocalcin 2in mice resulted in pre- and postnatal growth restriction, reducedbone and skeletal muscle growth, and organomegaly. Expression ofthis gene is induced by estrogen and altered in some breastcancers.
Background Reference 1:
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Background Reference 2:
Law, A.Y., et al. Exp. Cell Res. 316(3):466-476(2010)
Background Reference 3:
Volland, S., et al. Int. J. Cancer 125(9):2049-2057(2009)
Background Reference 4:
Ieta, K., et al. Int. J. Cancer 125(4):926-931(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-642

List Size:
400 ul

List Price:

$495.00

Datasheet
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