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Antibody used in WB on Human HepG2 at 5.0 ug/ml.
Antibody used in WB on Human HepG2 at 5.0 ug/ml.

STEAP3 Antibody

CATALOG NUMBER: 29-882

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STEAP3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
STEAP3 antibody can be used for detection of STEAP3 by ELISA at 1:312500. STEAP3 antibody can be used for detection of STEAP3 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
54 kDa, 55 kDa, 56 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store STEAP3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
STEAP3
Additional Names:
STEAP3, STMP3, TSAP6, dudlin-2, AHMIO2
Protein Accession Number:
NP_001008410
Protein Gi Number:
56549147
Ncbi Gene Id Number:
55240
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) and can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD (+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT
Background Reference 1:
Amzallag, N., (2004) J. Biol. Chem. 279 (44), 46104-46112.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-882

List Size:
100 ul

List Price:

$473.00

Datasheet
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