STRA6 Antibody

CATALOG NUMBER: 26-445

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STRA6.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
STRA6 antibody can be used for detection of STRA6 by ELISA at 1:62500. STRA6 antibody can be used for detection of STRA6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
73 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store STRA6 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
STRA6
Additional Names:
STRA6, FLJ12541, MCOPS9, PP14296, MCOPCB8
Protein Accession Number:
NP_071764
Protein Gi Number:
217330578
Ncbi Gene Id Number:
64220
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
STRA6 may act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). STRA6 acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. STRA6 binds to RBP/RBP4 with high affinity. STRA6 increases cellular retinol uptake from the retinol-RBP complex.
Background Reference 1:
Isken, A., (2008) Cell Metab. 7 (3), 258-268.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

26-445

List Size:
100 ul

List Price:

$519.00

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