STX4 Antibody

CATALOG NUMBER: 60-146

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of human STX4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
STX4
Additional Names:
Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A
Protein Accession Number:
Q12846
Protein Gi Number:
3041737
Ncbi Gene Id Number:
6810
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Background Reference 1:
Evesson, F.J., et al. J. Biol. Chem. 285(37):28529-28539(2010)
Background Reference 2:
Kennedy, M.J., et al. Cell 141(3):524-535(2010)
Background Reference 3:
Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
Background Reference 4:
Cooper, G.M., et al. Blood 112(4):1022-1027(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-146

List Size:
400 ul

List Price:

$495.00

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