STXBP1 Antibody

CATALOG NUMBER: 27-234

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STXBP1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
STXBP1 antibody can be used for detection of STXBP1 by ELISA at 1:12500. STXBP1 antibody can be used for detection of STXBP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Predicted Molecular Weight:
67 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store STXBP1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
STXBP1
Additional Names:
STXBP1, MUNC18-1, UNC18, hUNC18, rbSec1, P67, NSEC1, RBSEC1
Protein Accession Number:
NP_001027392
Protein Gi Number:
73760415
Ncbi Gene Id Number:
6812
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.
Background Reference 1:
Saitsu, H., (2008) Nat. Genet. 40 (6), 782-788.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-234

List Size:
100 ul

List Price:

$519.00

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