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Sufu (phospho Ser342) Antibody

CATALOG NUMBER: 79-513

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Sufu (Phospho-Ser342) antibody was raised against a peptide sequence around phosphorylation site of Serine 342 (A-P-S (p) -R-K) derived from Human Sufu.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
Predicted Molecular Weight:
54 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
SUFU
Additional Names:
SUFUH, SUFUXL, PRO1280, CFL, SUFUH
Protein Accession Number:
NP_057253.2
Protein Gi Number:
19923479
Ncbi Gene Id Number:
51684
Background:
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)
Background Reference 1:
Zimmern P, et al. (2010) Neurourol Urodyn. 29 (5): 715-8. Wang C, et al. (2010) Development. 137 (12): 2001-9. Rabasseda X. et al. (2010) Drug News Perspect. 23 (4): 273-5.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-513

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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