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Antibody used in IHC on Human kidney.
Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Antibody used in IHC on Human kidney.

SULF2 Antibody

CATALOG NUMBER: 26-392

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SULF2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
SULF2 antibody can be used for detection of SULF2 by ELISA at 1:312500. SULF2 antibody can be used for detection of SULF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
98 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SULF2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SULF2
Additional Names:
SULF2, DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
Protein Accession Number:
NP_061325
Protein Gi Number:
29789100
Ncbi Gene Id Number:
55959
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
Background Reference 1:
Uchimura, K., (er) BMC Biochem. 7, 2 (2006).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

26-392

List Size:
100 ul

List Price:

$473.00

Datasheet
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