SUV39H1 Antibody

CATALOG NUMBER: 27-610

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SUV39H1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SUV39H1 antibody can be used for detection of SUV39H1 by ELISA at 1:312500. SUV39H1 antibody can be used for detection of SUV39H1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
48 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SUV39H1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SUV39H1
Additional Names:
SUV39H1, KMT1A, MG44, SUV39H, H3-K9-HMTase 1
Protein Accession Number:
NP_003164
Protein Gi Number:
4507321
Ncbi Gene Id Number:
6839
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su (var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis.This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Kang, M.Y., (2007) Int. J. Cancer 121 (10), 2192-2197.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-610

List Size:
100 ul

List Price:

$473.00

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