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Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.

SUV39H1 Antibody

CATALOG NUMBER: 57-423

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SUV39H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SUV39H1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SUV39H1
Additional Names:
Histone-lysine N-methyltransferase SUV39H1, Histone H3-K9 methyltransferase 1, H3-K9-HMTase 1, Lysine N-methyltransferase 1A, Position-effect variegation 3-9 homolog, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1, SUV39H1, KMT1A, SUV39H
Protein Accession Number:
O43463
Ncbi Gene Id Number:
6839
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the suppressor of variegation 3-9homolog family and encodes a protein with a chromodomain and aC-terminal SET domain. This nuclear protein moves to thecentromeres during mitosis and functions as a histonemethyltransferase, methylating Lys-9 of histone H3. Overall, itplays a vital role in heterochromatin organization, chromosomesegregation, and mitotic progression.
Background Reference 1:
Chen, L., et al. EMBO J. 29(15):2538-2552(2010)
Background Reference 2:
Goyama, S., et al. Leukemia 24(1):81-88(2010)
Background Reference 3:
Cherrier, T., et al. Oncogene 28(38):3380-3389(2009)
Background Reference 4:
Li, Z., et al. J. Biol. Chem. 284(16):10361-10366(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-423

List Size:
400 ul

List Price:

$495.00

Datasheet
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