SUZ12 Antibody

CATALOG NUMBER: 27-619

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SUZ12.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SUZ12 antibody can be used for detection of SUZ12 by ELISA at 1:312500. SUZ12 antibody can be used for detection of SUZ12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1201 - HeLa Cell Lysate
Predicted Molecular Weight:
83 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SUZ12 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SUZ12
Additional Names:
SUZ12, CHET9, JJAZ1, KIAA0160
Protein Accession Number:
NP_056170
Protein Gi Number:
197333809
Ncbi Gene Id Number:
23512
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7;17) (p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Li, H., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (50), 20001-20006.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-619

List Size:
100 ul

List Price:

$519.00

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