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Antibody used in WB on Human HepG2 at 5.0 ug/ml.
Antibody used in WB on Human HepG2 at 5.0 ug/ml.

SWAP70 Antibody

CATALOG NUMBER: 30-175

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
69 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SWAP70 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SWAP70
Additional Names:
SWAP70, FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Accession Number:
NP_055870
Protein Gi Number:
93102364
Ncbi Gene Id Number:
23075
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Background Reference 1:
Liu, J., (2007) J. Histochem. Cytochem. 55 (7), 701-708.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-175

List Size:
100 ul

List Price:

$473.00

Datasheet
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