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Western blot analysis of SWAP70 using rabbit polyclonal SWAP70 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SWAP70 gene (Lane 2).
Western blot analysis of anti-SWAP70 Antibody in HepG2 cell line lysates (35ug/lane). SWAP70 was detected using the purified polyclonal antibody.
Western blot analysis of SWAP70 using rabbit polyclonal SWAP70 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SWAP70 gene (Lane 2).

SWAP70 Antibody

CATALOG NUMBER: 57-721

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SWAP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human SWAP70.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
69 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SWAP70
Additional Names:
Switch-associated protein 70, SWAP-70, SWAP70, KIAA0640
Protein Accession Number:
Q9UH65
Protein Gi Number:
74753323
Ncbi Gene Id Number:
23075
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SWAP70 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. This protein regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Background Reference 1:
Hilpel, et al., Mol. Biol. Cell 14(8):3242-3253 (2003).
Background Reference 2:
Rapalus, L., et al., Clin. Immunol. 101(3):270-275 (2001).
Background Reference 3:
Masat, L., et al., Proc. Natl. Acad. Sci. U.S.A. 97(5):2180-2184 (2000).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-721

List Size:
400 ul

List Price:

$495.00

Datasheet
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