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Western blot analysis in NCI-H460 cell line lysates (15ug/lane).
SYN3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in NCI-H460 cell line lysates (15ug/lane).

SYN3 Antibody

CATALOG NUMBER: 62-038

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SYN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-388 amino acids from the Central region of human SYN3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
63 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SYN3
Additional Names:
Synapsin-3, Synapsin III, SYN3
Protein Accession Number:
O14994
Ncbi Gene Id Number:
8224
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the synapsin gene family.Synapsins encode neuronal phosphoproteins which associate with thecytoplasmic surface of synaptic vesicles. Family members arecharacterized by common protein domains, and they are implicated insynaptogenesis and the modulation of neurotransmitter release,suggesting a potential role in several neuropsychiatric diseases.The protein encoded by this gene shares the synapsin family domainmodel, with domains A, C, and E exhibiting the highest degree ofconservation. The protein contains a unique domain J, locatedbetween domains C and E. Based on this gene's localization to22q12.3, a possible schizophrenia susceptibility locus, and theestablished neurobiological roles of the synapsins, this familymember may represent a candidate gene for schizophrenia. The TIMP3gene is located within an intron of this gene and is transcribed inthe opposite direction.
Background Reference 1:
Tsai, M.T., et al. Am. J. Med. Genet. 114(1):79-83(2002)
Background Reference 2:
Kao, H.T., et al. J. Exp. Zool. 285(4):360-377(1999)
Background Reference 3:
Porton, B., et al. J. Neurochem. 73(6):2266-2271(1999)
Background Reference 4:
Kao, H.T., et al. Proc. Natl. Acad. Sci. U.S.A. 95(8):4667-4672(1998)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-038

List Size:
400 ul

List Price:

$495.00

Datasheet
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