Synaptotagmin (phospho Thr202) Antibody

CATALOG NUMBER: 79-777

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synaptotagmin (phospho Thr202) antibody was raised against a peptide sequence around phosphorylation site of threonine 202 (R-K-T (p)-L-N) derived from Human Synaptotagmin.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of Synaptotagmin only when phosphorylated at threonine 202.
Predicted Molecular Weight:
60 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
SYT1
Additional Names:
LAG, LAP18, STN1, Prosolin, stathmin
Protein Accession Number:
NP_001129277.1
Protein Gi Number:
5032139
Ncbi Gene Id Number:
6857
Background:
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.
Background Reference 1:
E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107.
Background Reference 2:
Gry Houeland, J Neurophysiol, Jan 2007; 97: 134 - 143.
Background Reference 3:
Christelle Carteron, J. Cell Sci., Mar 2006; 119: 898 - 909.
Background Reference 4:
Vladimir I. Slepnev, Science, Aug 1998; 281: 821.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-777

List Size:
0.1 mg

List Price:

$376.00

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