TAC3 Antibody

CATALOG NUMBER: 57-679

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
13 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TAC3
Additional Names:
Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
Protein Accession Number:
Q9UHF0
Protein Gi Number:
18203501
Ncbi Gene Id Number:
6866
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the tachykinin family ofsecreted neuropeptides. The encoded protein is primarily expressedin the central and peripheral nervous system and functions as aneurotransmitter. This protein is the ligand for the neurokinin-3receptor. This protein is also expressed in the outersyncytiotrophoblast of the placenta and may be associated withpregnancy-induced hypertension and pre-eclampsia. Mutations in thisgene are associated with normosmic hypogonadotropic hypogonadism.Alternate splicing results in multiple transcript variants.
Background Reference 1:
Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
Background Reference 2:
Hrabovszky, E., et al. Eur. J. Neurosci. 31(11):1984-1998(2010)
Background Reference 3:
Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95(6):2857-2867(2010)
Background Reference 4:
Young, J., et al. J. Clin. Endocrinol. Metab. 95(5):2287-2295(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-679

List Size:
400 ul

List Price:

$495.00

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