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Human TACI/TNFRSF13B, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human BAFF, His Tag at 2 ug/mL (100 uL/well) can bind Human TACI/TNFRSF13B, Fc Tag with a linear range of 2-16 ng/mL (QC tested).
Immobilized Human APRIL, His,Flag Tag, active trimer at 1 ug/mL (100 uL/well) can bind Human TACI/TNFRSF13B, Fc Tag with a linear range of 0.8-25 ng/mL (Routinely tested).
Human TACI/TNFRSF13B, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

TACI/TNFRSF13B Recombinant Protein

CATALOG NUMBER: 11-531

Tested Applications:
ELISA, WB
Specifications
Source Species:
HEK293 cells
Species:
Human
Source Species:
HEK293 cells
Recombinant Protein Sequence:
Ser 2 - Thr 166
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.6 kDa. The protein migrates as 33-34 kDa, 35 kDa and 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Predicted Molecular Weight:
44.6 kDa
Purity:
>90% as determined by reduced SDS-PAGE.
Physical State:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Additional Names:
CD267,TACI,TNFRSF13B
Background:
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL.The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
Background Reference 1:
Dou, H., et al., 2016, Oncology Letters., 12(5), 3351–3355. (2) Van Attekum, M., 2016, Cell Death Discovery, 2, 16020 (3) Cole, M. B., 2016, Arthritis & Rheumatology (Hoboken, N.j.), 68(12), 2936–2944

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-531

List Size:
0.1 mg

List Price:

$455.00

Out of stock

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