TAF1A Antibody

CATALOG NUMBER: 58-292

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TAF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human TAF1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TAF1A
Additional Names:
TATA box-binding protein-associated factor RNA polymerase I subunit A, RNA polymerase I-specific TBP-associated factor 48 kDa, TAFI48, TATA box-binding protein-associated factor 1A, TBP-associated factor 1A, Transcription factor SL1, Transcription initiation factor SL1/TIF-IB subunit A, TAF1A
Protein Accession Number:
Q15573
Protein Gi Number:
74739864
Ncbi Gene Id Number:
9015
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Initiation of transcription by RNA polymerase I requiresthe formation of a complex composed of the TATA-binding protein(TBP) and three TBP-associated factors (TAFs) specific for RNApolymerase I. This complex, known as SL1, binds to the corepromoter of ribosomal RNA genes to position the polymerase properlyand acts as a channel for regulatory signals. This gene encodes thesmallest SL1-specific TAF. Two transcripts encoding differentisoforms have been identified.
Background Reference 1:
Greco-Stewart, V.S., et al. Virology 386(1):12-15(2009)
Background Reference 2:
Yamamoto, K., et al. Mol. Cell. Biol. 24(14):6338-6349(2004)
Background Reference 3:
Dynes, J.L., et al. J. Biochem. 135(3):429-438(2004)
Background Reference 4:
Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278(21):18953-18959(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-292

List Size:
400 ul

List Price:

$495.00

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