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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

TAF6 Antibody

CATALOG NUMBER: 57-846

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human TAF6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
73 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TAF6
Additional Names:
Transcription initiation factor TFIID subunit 6, RNA polymerase II TBP-associated factor subunit E, Transcription initiation factor TFIID 70 kDa subunit, TAF(II)70, TAFII-70, TAFII70, Transcription initiation factor TFIID 80 kDa subunit, TAF(II)80, TAFII-80, TAFII80, TAF6, TAF2E, TAFII70
Protein Accession Number:
P49848
Protein Gi Number:
1729810
Ncbi Gene Id Number:
6878
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes one of the smallersubunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. Alternative splicing results inmultiple transcript variants.
Background Reference 1:
Theisen, J.W., et al. Mol. Cell. Biol. (2010) In press :
Background Reference 2:
Wilhelm, E., et al. BMC Mol. Biol. 11, 10 (2010) :
Background Reference 3:
Wilhelm, E., et al. PLoS ONE(7), E2721 (2008) :
Background Reference 4:
Frontini, M., et al. Mol. Cell. Biol. 25(11):4638-4649(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-846

List Size:
400 ul

List Price:

$495.00

Datasheet
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