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Recombinant

Tafolecimab (PCSK9) – Research Grade Biosimilar

CATALOG NUMBER: 11-001

Clonality:
Recombinant Monoclonal
Conjugate:
Unconjugated
Specifications
source-species:
CHO cells
source-species:
CHO cells
Immunogen:
Homo sapiens / PCSK9 [Homo sapiens]
Conjugate:
Unconjugated
Purification:
>95%
Clonality:
Recombinant Monoclonal
Isotype:
IgG2-kappa
Buffer:
PBS buffer pH7.5
Concentration:
batch dependent
Storage Conditions:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.
Additional Names:
IBI-306
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GPRC5D / CD3 bispecific antibody is used to treat multiple myeloma. The bispecific antibody is commonly known as tafolecimab. It is constructed using the Duobody technology authorized by Genmab. The heavy chain of anti-CD3 antibody introduced F405L and R409K to construct the double antibody. S228P, F234A, and L235A mutations were simultaneously introduced into the IgG4 constant region.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

11-001

List Size:
0.1 mg

List Price:

$515.00

Datasheet
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