TARBP2 Antibody

CATALOG NUMBER: 57-481

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus
Immunogen:
This TARBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human TARBP2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TARBP2
Additional Names:
RISC-loading complex subunit TARBP2 {ECO:0000255, HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255, HAMAP-Rule:MF_03034}, TRBP
Protein Accession Number:
Q15633
Protein Gi Number:
209572714
Ncbi Gene Id Number:
6895
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
HIV-1, the causative agent of acquired immunodeficiencysyndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle.Activation of HIV-1 gene expression by the transactivator Tat isdependent on an RNA regulatory element (TAR) located downstream ofthe transcription initiation site. The protein encoded by this genebinds between the bulge and the loop of the HIV-1 TAR RNAregulatory element and activates HIV-1 gene expression in synergywith the viral Tat protein. Alternative splicing results inmultiple transcript variants encoding different isoforms. This genealso has a pseudogene.
Background Reference 1:
Garre, P., et al. Nat. Genet. 42(10):817-818(2010)
Background Reference 2:
Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
Background Reference 3:
Boni, V., et al. Pharmacogenomics J. (2010) In press :
Background Reference 4:
Wang, H.W., et al. Nat. Struct. Mol. Biol. 16(11):1148-1153(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-481

List Size:
400 ul

List Price:

$495.00

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