TAS1R1 Antibody

CATALOG NUMBER: 58-565

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TAS1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the Central region of human TAS1R1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
93 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TAS1R1
Additional Names:
Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1
Protein Accession Number:
Q7RTX1
Protein Gi Number:
57013075
Ncbi Gene Id Number:
80835
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a G protein-coupledreceptor and is a component of the heterodimeric amino acid tastereceptor T1R1+3. The T1R1+3 receptor responds to L-amino acids butnot to D-enantiomers or other compounds. Most amino acids that areperceived as sweet activate T1R1+3, and this activation is strictlydependent on an intact T1R1+3 heterodimer. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Fushan, A.A., et al. Chem. Senses 35(7):579-592(2010)
Background Reference 2:
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 3:
Prezeau, L., et al. Curr Opin Pharmacol 10(1):6-13(2010)
Background Reference 4:
Chandrashekar, J., et al. Nature 444(7117):288-294(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-565

List Size:
400 ul

List Price:

$495.00

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