TBC1D10B Antibody

CATALOG NUMBER: 59-373

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
87 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TBC1D10B
Additional Names:
TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B
Protein Accession Number:
Q4KMP7
Protein Gi Number:
294862492
Ncbi Gene Id Number:
26000
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Small G proteins of the RAB family (see MIM 179508)function in intracellular vesicle trafficking by switching from theGTP-bound state to the GDP-bound state with the assistance ofguanine nucleotide exchange factors (GEFs; see MIM 609700) andGTPase-activating proteins (GAPs). TBC1D10B functions as a GAP forseveral proteins of the Rab family (Ishibashi et al., 2009 [PubMed19077034]).
Background Reference 1:
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Background Reference 2:
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
Background Reference 3:
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-373

List Size:
400 ul

List Price:

$495.00

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