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Western blot analysis in CEM,K562 cell line lysates (35ug/lane).
Western blot analysis in CEM,K562 cell line lysates (35ug/lane).

TBCE Antibody

CATALOG NUMBER: 64-058

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
59 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TBCE
Additional Names:
Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE
Protein Accession Number:
Q15813
Protein Gi Number:
74762146
Ncbi Gene Id Number:
6905
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Background Reference 1:
Biernacki, M.A., et al. Cancer Res. 70(3):906-915(2010)
Background Reference 2:
Padidela, R., et al. J. Clin. Endocrinol. Metab. 94(8):2686-2691(2009)
Background Reference 3:
Lindgren, C.M., et al. PLoS Genet.(6), E1000508 (2009)
Background Reference 4:
Jin, S., et al. Development 136(9):1571-1581(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

64-058

List Size:
400 ul

List Price:

$495.00

Datasheet
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