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Antibody used in IHC on Human kidney.
Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Antibody used in IHC on Human kidney.

TBPL1 Antibody

CATALOG NUMBER: 28-345

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBPL1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
TBPL1 antibody can be used for detection of TBPL1 by ELISA at 1:312500. TBPL1 antibody can be used for detection of TBPL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
21 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TBPL1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TBPL1
Additional Names:
TBPL1, TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Accession Number:
NP_004856
Protein Gi Number:
4759234
Ncbi Gene Id Number:
9519
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Background Reference 1:
Martianov, I., et al., (2002) Development 129 (4), 945-955.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-345

List Size:
100 ul

List Price:

$473.00

Datasheet
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