TBR1 Antibody

CATALOG NUMBER: 59-440

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This TBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human TBR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TBR1
Additional Names:
T-box brain protein 1, T-brain-1, TBR-1, TES-56, TBR1
Protein Accession Number:
Q16650
Protein Gi Number:
2501122
Ncbi Gene Id Number:
10716
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of a conserved family of genes thatshare a common DNA-binding domain, the T-box. T-box genes encodetranscription factors involved in the regulation of developmentalprocesses. A similar protein has been disrupted in mice and shownto be critical for early cortical development, and causes loss ofprojection neurons in the olfactory bulbs and olfactory cortex. TheC-terminal region this similar protein was found to be necessaryand sufficient for association with the guanylate kinase domain ofcalcium/calmodulin-dependent serine protein kinase. [provided byRefSeq].
Background Reference 1:
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Background Reference 2:
Stefanovska, A.M., et al. Cancer Res. 61(22):8351-8352(2001)
Background Reference 3:
Hsueh, Y.P., et al. Nature 404(6775):298-302(2000)
Background Reference 4:
Bulfone, A., et al. Neuron 15(1):63-78(1995)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-440

List Size:
400 ul

List Price:

$495.00

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