TBX2 Antibody

CATALOG NUMBER: 59-016

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the Central region of human TBX2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
75 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TBX2
Additional Names:
T-box transcription factor TBX2, T-box protein 2, TBX2
Protein Accession Number:
Q13207
Protein Gi Number:
294862490
Ncbi Gene Id Number:
6909
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene product is the human homologof mouse Tbx2, and shares strong sequence similarity withDrosophila omb protein. Expression studies indicate that this genemay have a potential role in tumorigenesis as an immortalizingagent. Transcript heterogeneity due to alternative polyadenylationhas been noted for this gene.
Background Reference 1:
Vance, K.W., et al. Mol. Biol. Cell 21(15):2770-2779(2010)
Background Reference 2:
Radio, F.C., et al. Am. J. Med. Genet.152A (8), 2061-2066 (2010) :
Background Reference 3:
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Background Reference 4:
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-016

List Size:
400 ul

List Price:

$495.00

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