TBX4 Antibody

CATALOG NUMBER: 60-268

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Rat, Xenopus
Immunogen:
This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TBX4
Additional Names:
T-box transcription factor TBX4, T-box protein 4, TBX4
Protein Accession Number:
P57082
Protein Gi Number:
51338786
Ncbi Gene Id Number:
9496
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene is the human homolog of mouseTbx4, which is closely linked to Tbx2 on mouse chromosome 11.Similarly this gene, like TBX2, maps to human chromosome 17.Expression studies in mouse and chicken show that Tbx4 is expressedin developing hindlimb, but not in forelimb buds, suggesting a rolefor this gene in regulating limb development and specification oflimb identity.
Background Reference 1:
Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)
Background Reference 2:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 3:
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Background Reference 4:
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-268

List Size:
400 ul

List Price:

$495.00

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