TCF7L1 Antibody

CATALOG NUMBER: 25-004

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TCF7L1 antibody can be used for detection of TCF7L1 by ELISA at 1:312500. TCF7L1 antibody can be used for detection of TCF7L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
293T Cell Lysate
Predicted Molecular Weight:
63 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TCF7L1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TCF7L1
Additional Names:
TCF7L1, TCF-3, TCF3
Protein Accession Number:
NP_112573
Protein Gi Number:
13786123
Ncbi Gene Id Number:
83439
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Background Reference 1:
Hillier, L.W., (2005) Nature 434 (7034), 724-731.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-004

List Size:
100 ul

List Price:

$519.00

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