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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Antibody used in WB on Hum. Fetal Heart.
Antibody used in WB on Hum. Fetal Lung.
Antibody used in WB on Hum. Fetal Liver.
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

TCF7L2 Antibody

CATALOG NUMBER: 25-138

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TCF7L2 antibody can be used for detection of TCF7L2 by ELISA at 1:2500. TCF7L2 antibody can be used for detection of TCF7L2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Predicted Molecular Weight:
65 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TCF7L2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TCF7L2
Additional Names:
TCF7L2, TCF-4, TCF4
Protein Accession Number:
NP_110383
Protein Gi Number:
170014696
Ncbi Gene Id Number:
6934
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.
Background Reference 1:
Ren, Q., (2008) Diabetologia 51 (7), 1146-1152.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-138

List Size:
100 ul

List Price:

$519.00

Datasheet
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