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Western blot analysis of lysed extracts from 293 cells using TFE3 Antibody.
Western blot analysis of lysed extracts from 293 cells using TFE3 Antibody.

TFE3 Antibody

CATALOG NUMBER: 79-650

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
TFE3 antibody was raised against a peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous levels of total TFE3 protein.
Predicted Molecular Weight:
70 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
TFE3
Additional Names:
TFEA, RCCP2, RCCX1, bHLHe33, MAPTL, MTBT1, TAU, BHLHE33, TFEA
Protein Accession Number:
NP_006512.2
Protein Gi Number:
8659574
Ncbi Gene Id Number:
7030
Background:
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Background Reference 1:
Clark J., Lu Y. -J., Sidhar S. K., Parker C., Gill S., Oncogene 15:2233-2239 (1997) Weterman M. A. J., Wilbrink M., Proc. Natl. Acad. Sci. U. S. A. 93:15294-15298 (1996)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-650

List Size:
0.1 mg

List Price:

$370.00

Datasheet
Shipping Info

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