TFEB Antibody

CATALOG NUMBER: 28-949

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TFEB.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TFEB antibody can be used for detection of TFEB by ELISA at 1:312500. TFEB antibody can be used for detection of TFEB by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
53 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TFEB antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TFEB
Additional Names:
TFEB, TCFEB, BHLHE35, ALPHATFEB
Protein Accession Number:
NP_009093
Protein Gi Number:
24307933
Ncbi Gene Id Number:
7942
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21;q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Background Reference 1:
Argani, P., et al., (2005) Am. J. Surg. Pathol. 29 (2), 230-240.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-949

List Size:
100 ul

List Price:

$473.00

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