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TGF-alpha Recombinant Protein

CATALOG NUMBER: 40-117

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized TGF-alpha recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TGF-alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TGF-alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TGFA
Additional Names:
TFGA, Protransforming growth factor alpha, EGF-like TGF, TGF-alpha
Protein Accession Number:
NP_001093161.1
Protein Gi Number:
153791414
Ncbi Gene Id Number:
7039
Background:
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-117

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
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