TGF beta 1 Recombinant Protein

CATALOG NUMBER: 91-763

Specifications
source-species:
Human Cells
Species:
Human
source-species:
Human Cells
Recombinant Protein Sequence:
Ala279-Ser390
Fusion Tag:
Tag Free
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Predicted Molecular Weight:
12.8 kD
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.2 um filtered solution of 50mM Glycine 50mM NaCl pH4.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Storage Conditions:
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at -20°C for 3 months.
Ncbi Official Symbol:
TGFB1
Additional Names:
Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB
Protein Accession Number:
P01137
Ncbi Gene Id Number:
7040
Background:
Transforming Growth Factor beta -1 (TGF beta -1) is a secreted protein which belongs to the TGF- beta family. TGF beta -1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGF beta -1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGF beta -1 peptide. TGF beta -1 may also form heterodimers with other TGF beta family members. It has been found that TGF beta -1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

91-763

List Size:
0.05 mg

List Price:

$598.00

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