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Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Western Blot at 1:2000 dilution Lane 1: human testis lysate Lane 2: mouse lung lysate Lysates/proteins at 20 ug per lane.
Antibody staining TGFBR2 in Human spleen tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Western Blot at 1:2000 dilution Lane 1: NCCIT whole cell lysates Lane 2: mouse lung lysates Lane 3: SW620 whole cell lysates Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane.
Antibody staining TGFBR2 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).

TGFBR2 Antibody

CATALOG NUMBER: 56-081

Clonality:
Polyclonal
Tested Applications:
IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This TGFBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human TGFBR2.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC-P, WB
Application Note:
For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TGFBR2
Additional Names:
TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2
Protein Accession Number:
P37173
Protein Gi Number:
116242818
Ncbi Gene Id Number:
7048
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the Ser/Thr protein kinasefamily and the TGFB receptor subfamily. The encoded protein is atransmembrane protein that has a protein kinase domain, forms aheterodimeric complex with another receptor protein, and bindsTGF-beta. This receptor/ligand complex phosphorylates proteins,which then enter the nucleus and regulate the transcription of asubset of genes related to cell proliferation. Mutations in thisgene have been associated with Marfan Syndrome, Loeys-Deitz AorticAneurysm Syndrome, and the development of various types of tumors.Alternatively spliced transcript variants encoding differentisoforms have been characterized.
Background Reference 1:
Inamoto, S., et al. Cardiovasc. Res. 88(3):520-529(2010)
Background Reference 2:
Bianchini, G., et al. J. Clin. Oncol. 28(28):4316-4323(2010)
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Kim, J.N., et al. Toxicology 275 (1-3), 29-35 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-081

List Size:
400 ul

List Price:

$495.00

Datasheet
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