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Western blot analysis of anti- in Y79 cell line lysates (35ug/lane).
Western blot analysis of anti- in Y79 cell line lysates (35ug/lane).

TGIF Antibody

CATALOG NUMBER: 62-791

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This TGIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TGIF1
Additional Names:
Homeobox protein TGIF1, 5'-TG-3'-interacting factor 1, TGIF1, TGIF
Protein Accession Number:
Q15583
Protein Gi Number:
215274200
Ncbi Gene Id Number:
7050
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
Background Reference 1:
Pertile,K.K., Invest. Ophthalmol. Vis. Sci. 49 (1), 49-54 (2008)
Background Reference 2:
Chavarria-Siles,I., Mol. Psychiatry 12 (11), 1033-1041 (2007)
Background Reference 3:
Ferrand,N., FASEB J. 21 (2), 488-496 (2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-791

List Size:
400 ul

List Price:

$495.00

Datasheet
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