TGM3 Antibody

CATALOG NUMBER: 59-272

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TGM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-567 amino acids from the C-terminal region of human TGM3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
77 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TGM3
Additional Names:
Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG(E), TGE, TGase E, Transglutaminase-3, TGase-3, Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, TGM3
Protein Accession Number:
Q08188
Protein Gi Number:
257051080
Ncbi Gene Id Number:
7053
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Transglutaminases are enzymes that catalyze thecrosslinking of proteins by epsilon-gamma glutamyl lysineisopeptide bonds. While the primary structure of transglutaminasesis not conserved, they all have the same amino acid sequence attheir active sites and their activity is calcium-dependent. Theprotein encoded by this gene consists of two polypeptide chainsactivated from a single precursor protein by proteolysis. Theencoded protein is involved the later stages of cell envelopeformation in the epidermis and hair follicle.
Background Reference 1:
Yamane, A., et al. FEBS J. 277(17):3564-3574(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Negishi, A., et al. Cancer Sci. 100(9):1605-1611(2009)
Background Reference 4:
Fujimoto, A., et al. J. Hum. Genet. 54(8):461-465(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-272

List Size:
400 ul

List Price:

$495.00

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