THEX1 Antibody

CATALOG NUMBER: 29-513

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human THEX1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
THEX1 antibody can be used for detection of THEX1 by ELISA at 1:312500. THEX1 antibody can be used for detection of THEX1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1219 - MCF7 Cell Lysate
Predicted Molecular Weight:
40 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store THEX1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ERI1
Additional Names:
THEX1, 3'HEXO, MGC35395, HEXO, THEX1
Protein Accession Number:
NP_699163
Protein Gi Number:
31543184
Ncbi Gene Id Number:
90459
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).
Background Reference 1:
Kupsco, J.M., (2006) RNA 12 (12), 2103-2117.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-513

List Size:
100 ul

List Price:

$519.00

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