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Thrombopoeitin Recombinant Protein

CATALOG NUMBER: 40-454

Specifications
source-species:
E. coli
Species:
Murine
source-species:
E. coli
Recombinant Protein Sequence:
SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of human MO7e cells was found to be < 1.0 ng/mL, corresponding to a specific activity of > 1 x 106 units/mg.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Thrombopoeitin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Thrombopoeitin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Thrombopoeitin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Thpo
Additional Names:
Ml, Tpo, Mgdf, Mpllg, Thrombopoietin, C-mpl ligand, ML
Protein Accession Number:
NP_001166976.1
Protein Gi Number:
291045237
Ncbi Gene Id Number:
21832
Background:
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant murine TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-454

List Size:
0.002 mg, 0.01 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

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