Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 μg/ml.
Immunohistochemistry of TICRR in human small intestine tissue with TICRR antibody at 5 μg/mL.
Immunofluorescence of TICRR in human small intestine tissue with TICRR antibody at 20 μg/mL.
Western blot analysis of TICRR in human small intestine tissue lysate with TICRR antibody at 1 μg/ml.
Trial Size

TICRR Antibody

CATALOG NUMBER: 7857

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (74%)
Immunogen:
TICRR antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TICRR.
The immunogen is located within amino acids 1840 - 1890 of TICRR.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
TICRR antibody can be used for detection of TICRR by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificity:
TICRR antibody is human specific. At least two isoforms of TICRR are known to exist.
Positive Control 1:
Cat. No. 1308 - Human Small Intestine Tissue Lysate
Positive Control 2:
Cat. No. 11-801 - Human Small Intestine Tissue Slide
Predicted Molecular Weight:
Predicted: 210 kDa
Observed: 220 kDa
Purification:
TICRR antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
TICRR antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
TICRR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Ncbi Official Symbol:
TICRR
Additional Names:
TICRR Antibody: SLD3, Treslin, C15orf42, TopBP1-interacting checkpoint and replication regulator
Protein Accession Number:
NP_689472
Protein Gi Number:
118421085
Ncbi Gene Id Number:
90381
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TopBP1-interacting checkpoint and replication regulator, Treslin,chromosome 15 open reading frame 42, C15ORF42
Background Reference 1:
Sansam CL, Cruz NM, Danielian PS, et al. A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev. 2010; 24:183-94.
Background Reference 2:
Kumagai A, Shevchenko A, Shevchenko A, et al. Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J. Cell Biol. 2011;193:995-1007.
Background Reference 3:
Kumagai A, Shevchenko A, Shevchenko A, et al. Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell 2010; 140:349-59.
Background Reference 4:
Mueller AC, Keaton MA, and Dutta A. DNA replication: mammalian Treslin-TopBP1 interaction mirrors yeast Sld3-Dpb11. Curr. Biol. 2011; 21:R638-40.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

7857

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369